Oakley H. Crawford
P.O. Box 2008, 1060 Commerce Park, MS-6480
Oak Ridge National Laboratory
Oak Ridge, Tennessee 37831-6480
Phone: 865-574-5048
Fax: 865-241-1965
e-mail: crawfordoh@ornl.gov

Position:

Senior Staff Scientist

Appointed:

ORNL staff member since 1976

Education:

Ph.D., Physical Chemistry, University of Illinois, Urbana, 1966; Postdoctoral Fellow, Department of Applied Mathematics, Queen's University of Belfast, Northern Ireland, 1966-67

Previous positions:

Assistant and Associate Professor of Chemistry at Pennsylvania State University and Associate Professor of Chemistry at Barnard College

Professional activities:

Member, American Chemical Society, American Physical Society, Bohmische Physical Society, Radiation Research Society, Alpha Chi Sigma; Organizer of several international symposia and workshops

Primary expertise:

Computational protein structure, protein fold prediction

Research interests:

Genome-scale prediction of protein structure and function; protein structure determination from sparse NMR data, using models derived from threading; structure determination of protein complexes by combining small-angle neutron scattering data and docking calculations

Recent publications:

Approximately 130 publications and presentations, including:

Y. Xu, D. Xu, O.H. Crawford, J.R. Einstein 2000. "A computational method for NMR-constrained protein threading," J. Comp. Bio. 7(3-4): 449-467.

O.H. Crawford 2000. "Singleton score matrices for threading in the twilight zone," Fourth Community Wide Experiment on the Critical Assessment of Techniques for Protein Structure Predictions, Asilomar, CA USA, Dec. 3-7.

Y. Xu, D. Xu, O.H. Crawford, J.R. Einstein, F.W. Larimer, E.C. Uberbacher, M.A. Unseren, and G. Zhang 1999. "Protein threading by PROSPECT: a prediction experiment in CASP3," Protein Eng., 12(11): 899-907.

Crawford, O.H. 1999. "A fast, stochastic threading algorithm for proteins," Bioinformatics, 15 (1): 66-71.

W.E. Bolch, J.E. Turner, H. Yoshida, K.B. Jacobson, R.N. Hamm, and O.H. Crawford 1998. "Product yields from irradiated glycylglycine in oxygen-free solutions: Monte Carlo simulations and comparison with experiments," Radiat. Environ. Biophys., 37: -157-177.

O.H. Crawford 1997. "A Bayesian threading algorithm for protein fold recognition ," FASEB J. 11(9): A1039-A1039 Suppl. S Jul 31.